A database of hormones and their receptors |
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HMRbase accession number | 10162 |
Swiss-prot Accession number | Q5EDF9 (Sequence in FASTA format) |
Description | Thyroliberin precursor [Contains: Prothyroliberin; Thyroliberin(Thyrotropin-releasing hormone) (TRH) (Thyrotropin-releasing factor)(TRF) (TSH-releasing factor) (Protirelin)]. |
Source organism | Brachydanio rerio (Zebrafish) (Danio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the TRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems |
Protein Length | 199 Amino acids |
Molecular weight | 22739 |
References | 1 Zhang D., Jiang S.; "Molecular cloning and characterization of the thyrotropin-releasinghormone from zebrafish, Danio rerio."; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
2 Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. |
Domain Name | TRH |
Hormone Name | Thyroliberin |
Mature Hormone Sequence | QHP |
Position of mature hormone in Pre-Hormone protein | 3 Residues from position (64-66) |
Receptor | N/A |
Gene ID | 266721 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |